Attenuated Error-Related Potentials in Amyotrophic Lateral Sclerosis with Executive Dysfunctions

Highlights • We studied error monitoring in ALS patients and healthy controls (HC) using event related potential recordings. • Error-related negativities (Ne /ERN) did not generally differ between ALS and HC. • Ne /ERN amplitudes were associated with executive performance in ALS.

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Bibliographische Detailangaben
Veröffentlicht in:	Clinical neurophysiology 2017-08, Vol.128 (8), p.1496-1503
Hauptverfasser:	Seer, Caroline, Joop, Max, Lange, Florian, Lange, Christian, Dengler, Reinhard, Petri, Susanne, Kopp, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amyotrophic lateral sclerosis (ALS) Amyotrophic Lateral Sclerosis - diagnosis Amyotrophic Lateral Sclerosis - physiopathology Cognitive impairment Electroencephalography - methods Error(-related) negativity (Ne/ERN) Event-related potentials (ERP) Evoked Potentials - physiology Executive Function - physiology Executive functions Female Gyrus Cinguli - physiopathology Humans Male Middle Aged Nerve Net - physiopathology Neurology Photic Stimulation - methods Psychomotor Performance - physiology Reaction Time - physiology
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Beschreibung
Zusammenfassung:	Highlights • We studied error monitoring in ALS patients and healthy controls (HC) using event related potential recordings. • Error-related negativities (Ne /ERN) did not generally differ between ALS and HC. • Ne /ERN amplitudes were associated with executive performance in ALS.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2017.05.007