Evaluation of the InnoTyper® 21 Genotyping Kit in Multi-ethnic Populations

Highlights • Evaluation of the novel InnoTyper® 21 forensic genotyping kit for South African population groups. • Low frequency off-ladder allele in two Bantu groups reveals a third allele for locus RG148. • The power of discrimination of InnoTyper® 21 is greater than that obtained from the mitochon...

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Veröffentlicht in:	Forensic science international : genetics 2017-09, Vol.30, p.43-50
Hauptverfasser:	Ristow, Peter Gustav, Barnes, Nicole, Murphy, Gina Pineda, Brown, Hiromi, Cloete, Kevin W, D’Amato, Maria E
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa Alleles Amelogenin - genetics Bantu Binary markers Discriminant Analysis DNA Fingerprinting - instrumentation Ethnic Groups - genetics Genetics, Population Genotype Humans InnoTyper INNULS Microsatellite Repeats Pathology Sex Determination Analysis
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Zusammenfassung:	Highlights • Evaluation of the novel InnoTyper® 21 forensic genotyping kit for South African population groups. • Low frequency off-ladder allele in two Bantu groups reveals a third allele for locus RG148. • The power of discrimination of InnoTyper® 21 is greater than that obtained from the mitochondrial control region which is ideal for compromised biological material. • The HID parameters for InnoTyper® 21 outperformed both Investigator DIPplex® and GlobalFiler® with fragment sizes ≤ 125 bp.
ISSN:	1872-4973 1878-0326
DOI:	10.1016/j.fsigen.2017.06.002