Current and future therapies for advanced pancreatic cancer

Current and future therapies for advanced pancreatic cancer

Pancreatic cancer remains a deadly disease with a 5‐year survival rate of only 8%. Even after surgical resection, most patients have recurrence of their cancer. Over the last 10 years, improvements in chemotherapy regimens led to a doubling in median overall survival. Here we review the management o...

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Veröffentlicht in:Journal of surgical oncology 2017-07, Vol.116 (1), p.25-34
Hauptverfasser: Gupta, Rohan, Amanam, Idoroenyi, Chung, Vincent
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers, Tumor - analysis
CA-19-9 Antigen - analysis
Cancer Pain - therapy
Cancer surgery
Cancer therapies
Chemotherapy, Adjuvant
Clinical Trials as Topic
cytotoxic chemotherapy
Genetic Predisposition to Disease
Humans
Neoadjuvant Therapy
Neoplasm Staging
pancreas cancer
Pancreatic cancer
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - mortality
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - therapy
Risk Factors
vaccine therapy
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Beschreibung
Zusammenfassung:Pancreatic cancer remains a deadly disease with a 5‐year survival rate of only 8%. Even after surgical resection, most patients have recurrence of their cancer. Over the last 10 years, improvements in chemotherapy regimens led to a doubling in median overall survival. Here we review the management of advanced pancreatic cancer and highlight vaccine therapy as a novel modality of treatment.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.24623