Geographic variation in liver transplantation persists despite implementation of Share35
Aim Geographic disparities persist in the USA despite locoregional organ sharing policies. The impact of national organ sharing policies on waiting‐list mortality on a regional basis remains unknown. Methods Data on all adult liver transplants between 1 February 2002 and 31 March 2015 were obtained...
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Veröffentlicht in: | Hepatology research 2018-03, Vol.48 (4), p.225-232 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Aim
Geographic disparities persist in the USA despite locoregional organ sharing policies. The impact of national organ sharing policies on waiting‐list mortality on a regional basis remains unknown.
Methods
Data on all adult liver transplants between 1 February 2002 and 31 March 2015 were obtained from the United Network for Organ Sharing/Organ and Transplantation Network. Multivariable Cox proportional hazards models were constructed in a time‐to‐event analysis to estimate waiting‐list mortality for the pre‐ and post‐Share35 eras.
Results
In the analyzed time period, 134 247 patients were listed for transplantation and 54 510 received organs (42.8%). Listing volume increased following the introduction of the Share35 organ sharing policy (15 976 candidates pre‐ vs. 18 375 post) without significant regional changes as did the number of transplants (7210 pre‐ vs. 8224 post). Waiting‐list mortality improved from 12.2% to 8.1% (P |
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ISSN: | 1386-6346 1872-034X |
DOI: | 10.1111/hepr.12922 |