A European Multicientre Study on the Comparison of HIV-1 Viral Loads Between VERIS HIV-1 Assay and Roche COBAS® TAQMAN® HIV-1 test, Abbott RealTime HIV-1 Assay, and Siemens VERSANT HIV-1 Assay

Highlights • Extraction/amplification for HIV-1 RNA quantitation are integrated in one instrument. • Method comparison of HIV-1 viral load results demonstrated low bias below 1,000 cp/mL. • Patient results over time showed similar profiles and trending between methods. • Differing definitions of virologic failure level may cause confusion with patient management. • Care should be taken when changing systems as variability exists in assay results.