Cadmium, arsenic, selenium and iron– implications for tumor progression in breast cancer
Highlights • We analyzed contents of Cd, As, Se and Fe in 42 sets of breast cancer tissues. • Content of Cd, Se and Fe was significantly higher in tumors as compared to adjacent tissues. • Significant positive correlation between contents of Cd and As in tumors was found. • Cd content in tumors was...
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Veröffentlicht in: | Environmental toxicology and pharmacology 2017-07, Vol.53, p.151-157 |
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container_title | Environmental toxicology and pharmacology |
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creator | Jablonska, E Socha, K Reszka, E Wieczorek, E Skokowski, J Kalinowski, L Fendler, W Seroczynska, B Wozniak, M Borawska, M.H Wasowicz, W |
description | Highlights • We analyzed contents of Cd, As, Se and Fe in 42 sets of breast cancer tissues. • Content of Cd, Se and Fe was significantly higher in tumors as compared to adjacent tissues. • Significant positive correlation between contents of Cd and As in tumors was found. • Cd content in tumors was significantly associated with tumor stage, grade and progesterone status. • Low Se level in tumor tissues was significantly associated with the presence of metastases. |
doi_str_mv | 10.1016/j.etap.2017.05.014 |
format | Article |
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subjects | Adult Aged Aged, 80 and over Analytical methods Arsenic Arsenic - analysis Breast - chemistry Breast cancer Breast Neoplasms - chemistry Breast Neoplasms - pathology Cadmium Cadmium - analysis Cancer Emergency Female Health risks Humans Iron Iron - analysis Middle Aged Progesterone Selenium Selenium - analysis Smoking Tissues Tumors |
title | Cadmium, arsenic, selenium and iron– implications for tumor progression in breast cancer |
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