Resectable pancreatic adenocarcinoma: role of CT quantitative imaging biomarkers for predicting pathology and patient outcomes

Highlights • CT quantitative biomarkers can be helpful in the management of patients with pancreatic cancer. • Tumor attenuation measured at portal phase is associated with pathologic aggressiveness. • Texture and attenuation analysis can predict tumors associated with a worse prognosis. • CT quanti...

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Veröffentlicht in:	European journal of radiology 2017-05, Vol.90, p.152-158
Hauptverfasser:	Christophe, Cassinotto, Chong, Jaron, Zogopoulos, George, Reinhold, Caroline, Chiche, Laurence, Lafourcade, Jean-Pierre, Cuggia, Adeline, Terrebonne, Eric, Dohan, Anthony, Gallix, Benoît
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Adult Aged Biomarkers Cancer staging Carcinoma, Pancreatic Ductal - diagnostic imaging Carcinoma, Pancreatic Ductal - pathology CT attenuation value Disease-Free Survival Female Humans Lymph Nodes - pathology Male Middle Aged Multidetector Computed Tomography - methods Neoplasm Recurrence, Local - diagnostic imaging Neoplasm Recurrence, Local - pathology Pancreatic adenocarcinoma prognosis Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - pathology Prognosis Quantitative imaging biomarkers Radiology Retrospective Studies Texture analysis
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Zusammenfassung:	Highlights • CT quantitative biomarkers can be helpful in the management of patients with pancreatic cancer. • Tumor attenuation measured at portal phase is associated with pathologic aggressiveness. • Texture and attenuation analysis can predict tumors associated with a worse prognosis. • CT quantitative imaging biomarkers can improve the management of patients.
ISSN:	0720-048X 1872-7727
DOI:	10.1016/j.ejrad.2017.02.033