Conformation and dynamics of single polymer chain studied by optical microscopy techniques beyond the diffraction limit

The origin of the unique properties of a polymer material is the large entropic term of a single molecule, which has a chain-like structure with a large molecular weight. From the viewpoint of understanding the fundamental polymer physics, conformation of the single polymer chain is one of the most...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of electron microscopy 2017-08, Vol.66 (4), p.223-233
1. Verfasser: Aoki, Hiroyuki
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The origin of the unique properties of a polymer material is the large entropic term of a single molecule, which has a chain-like structure with a large molecular weight. From the viewpoint of understanding the fundamental polymer physics, conformation of the single polymer chain is one of the most important matters; however, it has been difficult to examine the behavior of a single chain because of the limitation of conventional experimental methods. Recent developments in optical microscopy allow the fluorescence imaging beyond the diffraction limit of light, and the author's group showed that the conformation and the dynamics of a single polymer chain can be examined by the high-resolution fluorescence imaging. This review presents the application of optical microscopy with nanometric spatial resolution to study the polymer materials at the single-chain level.
ISSN:0022-0744
2050-5701
1477-9986
DOI:10.1093/jmicro/dfx016