Comparative incidence dynamics and serotypes of meningitis, bacteremic pneumonia and other-IPD in young children in the PCV era: Insights from Israeli surveillance studies

Highlights • PCV7/13 impact on meningitis, bacteremic-pneumonia (BP) and other-IPD differed. • In all 3 entities, disease caused by PCV13 serotypes (VT13) declined by ∼90%. • Diseases caused by non-VT13 increased by 256%, 302% and 116%, respectively. • Meningitis patients were younger; BP had higher...

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Veröffentlicht in:	Vaccine 2018-08, Vol.36 (36), p.5477-5484
Hauptverfasser:	Ben-Shimol, Shalom, Givon-Lavi, Noga, Grisaru-Soen, Galia, Megged, Orli, Greenberg, David, Dagan, Ron
Format:	Artikel
Sprache:	eng
Schlagworte:	Age composition Allergy and Immunology Cerebrospinal fluid Children Dynamics Health maintenance organizations HMOs Illnesses Incidence IPD – invasive pneumococcal disease Meningitis Pathogenesis PCV – pneumococcal conjugate vaccine Pediatrics Pneumonia Population Sepsis Serotypes Streptococcus infections Surveillance Vaccines
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