Fast, solvent-free and highly enantioselective fluorination of β-keto esters catalyzed by chiral copper complexes in a ball mill

Fast, solvent-free and highly enantioselective fluorination of β-keto esters catalyzed by chiral copper complexes in a ball mill

A fast and highly enantioselective fluorination of beta -keto esters catalyzed by diphenylamine linked bis(oxazoline)-Cu(OTf)2 complexes under solvent-free conditions has been developed using a planetary ball mill. High yields, high enantioselectivities and shorter reaction times were achieved with...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Green chemistry : an international journal and green chemistry resource : GC 2017-04, Vol.19 (7), p.1674-1677
Hauptverfasser: Wang, Yifeng, Wang, Haojiang, Jiang, Yidong, Zhang, Cheng, Shao, Juanjuan, Xu, Danqian
Format: Artikel
Sprache:eng
Schlagworte:
Ball milling
Catalysts
Coordination compounds
Copper
Esters
Fluorination
Reaction time
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A fast and highly enantioselective fluorination of beta -keto esters catalyzed by diphenylamine linked bis(oxazoline)-Cu(OTf)2 complexes under solvent-free conditions has been developed using a planetary ball mill. High yields, high enantioselectivities and shorter reaction times were achieved with low catalyst loading.
ISSN:1463-9262
1463-9270
DOI:10.1039/c6gc03306g