Post-marketing safety surveillance for inactivated and live-attenuated Japanese encephalitis vaccines in China, 2008–2013

Highlights • Both an inactivated Japanese encephalitis vaccine (JE-I) and live-attenuated Japanese encephalitis vaccine (JE-L) are used in China, JE-L, produced by a Chinese manufacturer, was prequalified by WHO in 2013. • Passive adverse events surveillance for JE-I and JE-L vaccines in China from...

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Veröffentlicht in:Vaccine 2017-06, Vol.35 (29), p.3666-3671
Hauptverfasser: Wu, Wendi, Liu, Dawei, Li, Keli, Nuorti, J. Pekka, Nohynek, Hanna M, Xu, Disha, Ye, Jiakai, Zheng, Jingshan, Wang, Huaqing
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Sprache:eng
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Zusammenfassung:Highlights • Both an inactivated Japanese encephalitis vaccine (JE-I) and live-attenuated Japanese encephalitis vaccine (JE-L) are used in China, JE-L, produced by a Chinese manufacturer, was prequalified by WHO in 2013. • Passive adverse events surveillance for JE-I and JE-L vaccines in China from 2008 to 2013 did not identify apparent safety soncerns. • Further study should evaluate JE-I and febrile convulsion, discern effects of concurrent vaccination with other vaccines, and employ more sensitive signal detection methods.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2017.05.021