Short- and long-term outcomes after non-severe acute kidney injury

Background Severe acute kidney injury (AKI) is associated with chronic kidney disease (CKD), cardiovascular events and increased mortality. However, little is known about the prognosis in hospitalized population suffering from non-severe AKI episodes. The aim of this study is to determine the impact...

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Veröffentlicht in:Clinical and experimental nephrology 2018-02, Vol.22 (1), p.61-67
Hauptverfasser: Arias-Cabrales, Carlos, Rodríguez, Eva, Bermejo, Sheila, Sierra, Adriana, Burballa, Carla, Barrios, Clara, Soler, María José, Pascual, Julio
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Sprache:eng
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Zusammenfassung:Background Severe acute kidney injury (AKI) is associated with chronic kidney disease (CKD), cardiovascular events and increased mortality. However, little is known about the prognosis in hospitalized population suffering from non-severe AKI episodes. The aim of this study is to determine the impact of non-severe AKI episodes in cardiovascular events, mortality and CKD, on short and long term. Methods Retrospective cohort study to 360 patients who met the criteria for diagnosis of AKI according ADQI guidelines with full recovery of renal function after the AKI episode, admitted between January 2000 and December 2010 in our hospital. Follow-up was 4 years after the diagnosis of AKI. Covariates included demographic variables, baseline creatinine and diagnosis of comorbidities. Results 360 AKI survivor patients were included. Twenty five of them (6.7%) had developed CKD after 1-year follow-up. Hypertension (OR 1.62; 95% CI 1.2–2.6, p  2.6 mg/dL in AKI (OR 1.7; 95% CI 1.2–3.7, p  66 years was an independent risk factor (OR 1.03, 95% CI 1.03–1.06, p  
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-017-1420-y