Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory
Highlights • Maternal separation caused learning and memory impairment. • Fluvoxamine maleate (FM) reversed learning and memory impairment. • FM protected DA and 5-HT signaling in the prefrontal cortex.
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| Veröffentlicht in: | Brain research bulletin 2017-06, Vol.132, p.75-81 |
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| container_title | Brain research bulletin |
| container_volume | 132 |
| creator | Dallé, Ernest Daniels, Willie M.U Mabandla, Musa V |
| description | Highlights • Maternal separation caused learning and memory impairment. • Fluvoxamine maleate (FM) reversed learning and memory impairment. • FM protected DA and 5-HT signaling in the prefrontal cortex. |
| doi_str_mv | 10.1016/j.brainresbull.2017.05.014 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0361-9230 |
| ispartof | Brain research bulletin, 2017-06, Vol.132, p.75-81 |
| issn | 0361-9230 1873-2747 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Cognitive impairment Corticosterone - blood Dopamine Dopamine - metabolism Fluvoxamine - pharmacology Learning - drug effects Learning - physiology Learning Disorders - drug therapy Learning Disorders - metabolism Lipid Peroxidation - drug effects Lipid Peroxidation - physiology Male Maternal Deprivation Memory - drug effects Memory - physiology Memory Disorders - drug therapy Memory Disorders - metabolism Neurology Neurotransmitter Agents - pharmacology Nootropic Agents - pharmacology Oxidopamine Parkinsonian Disorders - drug therapy Parkinsonian Disorders - metabolism Parkinsonian Disorders - psychology Parkinson’s disease Prefrontal cortex Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Random Allocation Rats, Sprague-Dawley Serotonin Serotonin - metabolism Stress, Psychological - metabolism |
| title | Fluvoxamine maleate effects on dopamine signaling in the prefrontal cortex of stressed Parkinsonian rats: Implications for learning and memory |
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