The Expression of MCM7 is a Useful Biomarker in the Early Diagnostic of Gastric Cancer

The Expression of MCM7 is a Useful Biomarker in the Early Diagnostic of Gastric Cancer

The aim of this study was to investigate the expression of minichromosome maintenance complex component 7 (MCM7) in gastric mucosal lesions, further to find its potential effect as a biomarker to distinguish intraepithelial neoplasia from gastric mucosal lesions. MCM7 and Ki67 were detected in 93 ca...

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Veröffentlicht in:Pathology oncology research 2018-04, Vol.24 (2), p.367-372
Hauptverfasser: Yang, Jing-yan, Li, Dong, Zhang, Yuan, Guan, Bing-xin, Gao, Ping, Zhou, Xing-chen, Zhou, Cheng-jun
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cell cycle
Cloning
Differential diagnosis
Gastric cancer
Immunohistochemistry
Immunology
Lesions
Medical diagnosis
Medical prognosis
Mucosa
Oncology
Original Article
Pathology
Reagents
Tumor cells
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Zusammenfassung:The aim of this study was to investigate the expression of minichromosome maintenance complex component 7 (MCM7) in gastric mucosal lesions, further to find its potential effect as a biomarker to distinguish intraepithelial neoplasia from gastric mucosal lesions. MCM7 and Ki67 were detected in 93 cases of gastric mucosal lesions by immunohistochemistry. MCM7 and Ki67 expression in GT were lowest compared with other groups ( P
ISSN:1219-4956
1532-2807
DOI:10.1007/s12253-017-0251-1