Cytogenetic Biomonitoring in Buccal Mucosal Cells from Municipal Solid Waste Collectors

Waste collectors collect, transport, and process the garbage produced by people living in the city. Nowadays, this activity requires special attention due to the environmental impact of garbage and its potential consequences on human health. The aim of this study was to evaluate potential cytotoxic...

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Veröffentlicht in:Anticancer research 2017-02, Vol.37 (2), p.849-852
Hauptverfasser: Andrade, Mariana Carvalho, Dos Santos, Jean Nunes, Cury, Patricia Ramos, Flygare, Ana Carolina Correa, Claudio, Samuel Rangel, Oshima, Celina Tizuko Fujiyama, Ribeiro, Daniel Araki
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Sprache:eng
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Zusammenfassung:Waste collectors collect, transport, and process the garbage produced by people living in the city. Nowadays, this activity requires special attention due to the environmental impact of garbage and its potential consequences on human health. The aim of this study was to evaluate potential cytotoxic and mutagenic effects of garbage collection on waste collectors. For this purpose, a total of 47 male waste collectors aged from 24 to 53 years were included in the experimental group. A total of 30 men matched by age were used as the control group. Cytotoxicity and mutagenicity were analyzed by micronucleus test in buccal mucosaI cells. No statistically significant difference (p>0.05) in the frequency of micronuclei was detected in the waste collectors when compared to controls. Nevertheless, higher frequencies of karyolysis and pyknosis (p
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.11388