Maternal Serum PAPP-A as an Early Marker of Obstetric Complications?

Objective: The aim of this study was to investigate whether low first-trimester PAPP-A levels are associated with an adverse pregnancy outcome. Materials and Methods: A retrospective case-control study was carried out using a Down's syndrome assays database over a 6-year period, between the 8th...

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Veröffentlicht in:	Fetal diagnosis and therapy 2015-01, Vol.37 (1), p.33-36
Hauptverfasser:	Quattrocchi, Tommasa, Baviera, Giovanni, Pochiero, Teresa, Basile, Francesca, Rizzo, Laura, Santamaria, Angelo, Corrado, Francesco, D'Anna, Rosario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological markers Biomarkers - blood Case-Control Studies Diabetes, Gestational - blood Diabetes, Gestational - diagnosis Diagnosis Down Syndrome - blood Down Syndrome - diagnosis Female Glycoproteins Health aspects Humans Infant, Newborn Obstetrical research Original Paper Pre-Eclampsia - blood Pre-Eclampsia - diagnosis Pregnancy Pregnancy Outcome Pregnancy Trimester, First - blood Pregnancy, Complications of Pregnancy-Associated Plasma Protein-A - metabolism Retrospective Studies Risk factors Young Adult
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Beschreibung
Zusammenfassung:	Objective: The aim of this study was to investigate whether low first-trimester PAPP-A levels are associated with an adverse pregnancy outcome. Materials and Methods: A retrospective case-control study was carried out using a Down's syndrome assays database over a 6-year period, between the 8th and 11th week of pregnancy. There were 164 women with PAPP-A multiples of median (MoM) levels
ISSN:	1015-3837 1421-9964
DOI:	10.1159/000365147