Ventricular Premature Complex Induced or Ventricular Premature Complex Worsened Cardiomyopathy

Recent studies have focused on identifying the predictors of VPC-induced cardiomyopathy, with the most consistent predictors being VPC burden, VPC QRS duration, asymptomatic VPSs, pleomorphic VPCs, or epicardial origin.4,5 A frequency greater than 10% has been suggested as a good indicator of response to radiofrequency ablation.6 It usually resolves within 4 months of successful ablation in most patients but can take up to 4 years.7 Therefore, initial work-up for all symptomatic or asymptomatic patients with frequent VPCs should include an objective VPC burden assessment and an assessment of cardiac function by left ventricular (LV) ejection fraction (EF). Because the LVEF is difficult to assess in patients with incessant bigeminy/frequent VPCs, the question remains whether LV dysfunction and subsequent improvement in LVEF postablation are real in all cases or are observed because of inadequate assessment of LVEF in the most cases.8 Therefore, it has been recommended to perform echocardiography immediately postablation...