Risk of low birth weight and micronutrient deficiencies in neonates from mothers after gastric bypass: A case control study

Abstract Background An increased risk of small-for-gestational-age infants after maternal bariatric surgery has been shown. The risk of micronutrients deficiencies in these neonates is unclear. Objective To screen for micronutrients deficiencies in newborns of mothers with gastric bypass Settings University Hospital in Angers, France Methods This study compared the clinical and cord blood biological characteristics of 56 newborns of mothers with prior gastric bypass (RYGB) and 56 newborns of non-obese healthy mothers after normal pregnancy (controls), followed between 01/03/2008 and 31/10/2012. Cord blood micronutrients concentrations from controls were used for establishing normative data. After RYGB, the women took daily micronutrients supplements. Results RYGB mothers lost 18.1±6.3 kg/m2 of Body Mass Index (BMI) in the 11-69 months between surgery and pregnancy onset (percentage of excess weight loss 79±20%), reaching BMI of 30.1±6.0 kg/m2 compared with 22.3±4.0 kg/m2 in the controls (p