Hyperoside protects against chronic mild stress-induced learning and memory deficits
Highlights • Hyperoside enhances learning and memory in CMS rats. • The protective mechanism of hyperoside might be related to the regulation of BDNF. • Hyperoside-enriched diets may contribute to prevent and treat stress-related diseases.
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| Veröffentlicht in: | Biomedicine & pharmacotherapy 2017-07, Vol.91, p.831-840 |
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| container_title | Biomedicine & pharmacotherapy |
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| creator | Gong, Yeli Yang, Youhua Chen, Xiaoqing Yang, Min Huang, Dan Yang, Rong Zhou, Lianying Li, Changlei Xiong, Qiuju Xiong, Zhe |
| description | Highlights • Hyperoside enhances learning and memory in CMS rats. • The protective mechanism of hyperoside might be related to the regulation of BDNF. • Hyperoside-enriched diets may contribute to prevent and treat stress-related diseases. |
| doi_str_mv | 10.1016/j.biopha.2017.05.019 |
| format | Article |
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| language | eng |
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| subjects | Animals BDNF Brain-Derived Neurotrophic Factor - metabolism Carbazoles - pharmacology Chronic Disease Chronic mild stress Cognition - drug effects Corticosterone - blood Depression - blood Depression - complications Depression - drug therapy Depression - physiopathology Hippocampus - metabolism Hyperoside Indole Alkaloids - pharmacology Internal Medicine Learning - drug effects Learning and memory Male Maze Learning - drug effects Medical Education Memory Disorders - blood Memory Disorders - drug therapy Memory Disorders - etiology Memory Disorders - physiopathology Neuroprotective Agents - chemistry Neuroprotective Agents - pharmacology Neuroprotective Agents - therapeutic use Quercetin - analogs & derivatives Quercetin - chemistry Quercetin - pharmacology Quercetin - therapeutic use Rats, Sprague-Dawley Receptor, trkB - metabolism Stress, Psychological - blood Stress, Psychological - complications Stress, Psychological - physiopathology |
| title | Hyperoside protects against chronic mild stress-induced learning and memory deficits |
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