Decreased body mass index is associated with impaired survival in lung cancer patients with brain metastases: A retrospective analysis of 624 patients

Body mass index (BMI) is a prognostic factor in several cancer types. We investigated the prognostic role of BMI in a large patient cohort with newly diagnosed lung cancer brain metastases (BM) between 1990 and 2013. BMI at diagnosis of BM and graded prognostic assessment (GPA) were calculated. Defi...

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Veröffentlicht in:	European journal of cancer care 2017-11, Vol.26 (6), p.e12707-n/a
Hauptverfasser:	Masel, E.K., Berghoff, A.S., Füreder, L.M., Heicappell, P., Schlieter, F., Widhalm, G., Gatterbauer, B., Dieckmann, U., Birner, P., Bartsch, R., Schur, S., Watzke, H.H., Zielinski, C.C., Preusser, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Body mass Body Mass Index Body size Body weight Brain Brain cancer Brain Neoplasms - secondary cachexia Cancer Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - secondary Comorbidity Diagnosis Female Histology Humans Life expectancy Lung cancer lung neoplasms Lung Neoplasms - mortality Lung Neoplasms - pathology Male Medical prognosis Metastases Metastasis Middle Aged Multivariate Analysis neoplasm metastasis Non-small cell lung carcinoma Nursing Overweight Overweight - epidemiology palliative care Patients Prognosis Proportional Hazards Models quality of life Regression analysis Regression models Retrospective Studies Small Cell Lung Carcinoma - mortality Small Cell Lung Carcinoma - secondary Survival Survival Rate Thinness - epidemiology Underweight
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Zusammenfassung:	Body mass index (BMI) is a prognostic factor in several cancer types. We investigated the prognostic role of BMI in a large patient cohort with newly diagnosed lung cancer brain metastases (BM) between 1990 and 2013. BMI at diagnosis of BM and graded prognostic assessment (GPA) were calculated. Definitions were underweight (BMI
ISSN:	0961-5423 1365-2354
DOI:	10.1111/ecc.12707