Synthesis of 4‑Halo-3(2H)‑furanones Using Intramolecular Cyclization of Sulfonium Salts
A simple and efficient synthesis of 4-halo-3(2H)-furanones by halogenative intramolecular cyclization of sulfonium salts is described, which can expedite the production of a variety of 4-bromo- or 4-iodo-3(2H)-furanones, useful synthetic building blocks, in good to high yield under mild conditions...
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| Veröffentlicht in: | Journal of organic chemistry 2017-06, Vol.82 (11), p.5583-5589 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A simple and efficient synthesis of 4-halo-3(2H)-furanones by halogenative intramolecular cyclization of sulfonium salts is described, which can expedite the production of a variety of 4-bromo- or 4-iodo-3(2H)-furanones, useful synthetic building blocks, in good to high yield under mild conditions. |
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| ISSN: | 0022-3263 1520-6904 |
| DOI: | 10.1021/acs.joc.7b00399 |