Quinolone Ear Drops After Tympanostomy Tubes and the Risk of Eardrum Perforation: A Retrospective Cohort Study

Quinolone Ear Drops After Tympanostomy Tubes and the Risk of Eardrum Perforation: A Retrospective Cohort Study

Background. This study investigated whether quinolone ear drops, with or without corticosteroids, increase the risk of perforation requiring tympanoplasty following tympanostomy tube (TT) placement in children. Methods. This was a retrospective cohort study using Medicaid encounter and pharmacy bill...

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Veröffentlicht in:Clinical infectious diseases 2017-04, Vol.64 (8), p.1052-1058
Hauptverfasser: Alrwisan, Adel, Antonelli, Patrick J., Winterstein, Almut G.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - adverse effects
Antibiotics
ARTICLES AND COMMENTARIES
Child
Child, Preschool
Children & youth
Ear diseases
Eardrum
Female
Humans
Infant
Infant, Newborn
Male
Medical treatment
Middle Ear Ventilation
Otitis Media - complications
Otitis Media - therapy
Quinolones - administration & dosage
Quinolones - adverse effects
Regression analysis
Retrospective Studies
Risk assessment
Treatment Outcome
Tympanic Membrane Perforation - prevention & control
United States
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Zusammenfassung:Background. This study investigated whether quinolone ear drops, with or without corticosteroids, increase the risk of perforation requiring tympanoplasty following tympanostomy tube (TT) placement in children. Methods. This was a retrospective cohort study using Medicaid encounter and pharmacy billing data from 29 US states between 1999 and 2006. Children
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/cix032