Immunoexpression of HDAC1, HDAC2, and HAT1 in actinic cheilitis and lip squamous cell carcinoma

Background Acetylation and deacetylation are the most studied covalent histone modifications resulting in transcriptional regulation with histone deacetylases (HDAC) and histone acetyltransferases (HAT) as the main associated enzymes. These enzymes overexpression induces abnormal transcription of ke...

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Veröffentlicht in:	Oral diseases 2017-05, Vol.23 (4), p.505-510
Hauptverfasser:	Chrun, ES, Modolo, F, Vieira, DSC, Borges‐Júnior, ÁLS, Castro, RG, Daniel, FI
Format:	Artikel
Sprache:	eng
Schlagworte:	actinic cheilitis Adolescent Adult Aged Aged, 80 and over Biomarkers, Tumor - metabolism Carcinoma, Squamous Cell - enzymology Case-Control Studies Cheilitis - enzymology Child Child, Preschool Dentistry DNA Modification Methylases - metabolism Female histone acetyltransferases Histone Acetyltransferases - metabolism Histone Deacetylase 1 - metabolism Histone Deacetylase 2 - metabolism histone deacetylases Humans Immunohistochemistry Lip Neoplasms - enzymology lip neoplasms Male Middle Aged squamous cell carcinoma Young Adult
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