Regeneration of jejunal wall defect using an implant based on silk fibroin fibers

Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery, we observed recovery of all layers of the jejunum wall at the site of injury and complete...

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Veröffentlicht in:	Doklady. Biochemistry and biophysics 2017, Vol.472 (1), p.12-14
Hauptverfasser:	Moisenovich, M. M., Kulikov, D. A., Goncharenko, A. V., Arkhipova, A. Y., Vasiljeva, T. V., Filyushkin, Yu. N., Arkhipova, L. V., Kotlyarova, M. S., Kulikov, A. V., Mashkov, A. E., Agapov, I. I., Kirpichnikov, M. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Bone Marrow Cells - drug effects Bone Marrow Cells - physiology Cells Fibers Fibroins - adverse effects Fibroins - chemistry Guided Tissue Regeneration - methods Implants, Experimental Jejunum - physiology Jejunum - surgery Life Sciences Male Molecular Biology Rats Rats, Wistar Regeneration Tissue Scaffolds - adverse effects Tissue Scaffolds - chemistry Transplants & implants
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Zusammenfassung:	Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery, we observed recovery of all layers of the jejunum wall at the site of injury and complete degradation of the implant material.
ISSN:	1607-6729 1608-3091
DOI:	10.1134/S1607672917010045