Comparative measurement of ghrelin, leptin, adiponectin, EGF and IGF-1 in breast milk of mothers with overweight/obese and normal-weight infants

Comparative measurement of ghrelin, leptin, adiponectin, EGF and IGF-1 in breast milk of mothers with overweight/obese and normal-weight infants

Background/Objectives: Obese infants are more susceptible to develop adulthood obesity and its related comorbidities. Previous studies have shown the presence of hormones and growth factors in maternal breast milk that may influence infant adiposity. The aim of this study was to investigate differen...

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Veröffentlicht in:European journal of clinical nutrition 2015-05, Vol.69 (5), p.614-618
Hauptverfasser: Khodabakhshi, A, Ghayour-Mobarhan, M, Rooki, H, Vakili, R, Hashemy, S-I, Mirhafez, S R, Shakeri, M-T, Kashanifar, R, Pourbafarani, R, Mirzaei, H, Dahri, M, Mazidi, M, Ferns, G, Safarian, M
Format: Artikel
Sprache:eng
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Adiponectin
Adiponectin - analysis
Adipose tissue
Adult
Anthropometry
Babies
Baby foods
Body weight
Body Weight - physiology
Breast
Breast Feeding
Breast milk
Breastfeeding & lactation
Case-Control Studies
Chemical properties
Child Development - physiology
Childhood obesity
Clinical Nutrition
Correlation analysis
Cross-Sectional Studies
Cytokines
Enzyme-linked immunosorbent assay
Epidemiology
Epidermal Growth Factor - analysis
Female
Fibroblast growth factor 2
Food and nutrition
Ghrelin
Ghrelin - analysis
Growth factors
Health aspects
Hormones
Humans
Infant
Infant Nutritional Physiological Phenomena
Infants
Insulin
Insulin-like growth factor I
Insulin-Like Growth Factor I - analysis
Insulin-like growth factors
Internal Medicine
Leptin
Leptin - analysis
Measurement methods
Medicine
Medicine & Public Health
Metabolic Diseases
Milk
Milk, Human - chemistry
Mothers
Obesity
Obesity - epidemiology
original-article
Overweight
Overweight - epidemiology
Overweight - etiology
Physiological aspects
Pregnancy
Public Health
Testing
Weight
Young Adult
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Zusammenfassung:Background/Objectives: Obese infants are more susceptible to develop adulthood obesity and its related comorbidities. Previous studies have shown the presence of hormones and growth factors in maternal breast milk that may influence infant adiposity. The aim of this study was to investigate differences in concentrations of three hormones and two growth factors in the breast milk of mothers with obese and non-obese infants. Subjects/Methods: In this cross-sectional study, 40 mothers with overweight or obese infants (weight for length percentile >97) and 40 age-matched mothers with normal-weight infant (−10
ISSN:0954-3007
1476-5640
DOI:10.1038/ejcn.2014.205