High serum leptin levels in infancy can potentially predict obesity in childhood, especially in formula-fed infants

High serum leptin levels in infancy can potentially predict obesity in childhood, especially in formula-fed infants

Aim To investigate serum leptin levels in breast‐fed and formula‐fed infants in infancy and their possible relationship to body mass index (BMI) in childhood. Methods We enrolled 237 healthy term infants between September 2000 and April 2004 and tested their serum leptin levels, took anthropometric...

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Veröffentlicht in:Acta Paediatrica 2013-10, Vol.102 (10), p.e455-e459
Hauptverfasser: Savino, F, Liguori, SA, Benetti, S, Sorrenti, M, Fissore, MF, Cordero di Montezemolo, L
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Biomarkers - blood
Body Mass Index
Breast Feeding
Breastfeeding
Child
Childhood
Decision Support Techniques
Female
Follow-Up Studies
Humans
Infancy
Infant
Infant Formula
Leptin
Leptin - blood
Linear Models
Male
Multivariate Analysis
Pediatric Obesity - blood
Pediatric Obesity - diagnosis
Pediatric Obesity - etiology
Pediatric Obesity - prevention & control
Risk Factors
Sex Factors
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Zusammenfassung:Aim To investigate serum leptin levels in breast‐fed and formula‐fed infants in infancy and their possible relationship to body mass index (BMI) in childhood. Methods We enrolled 237 healthy term infants between September 2000 and April 2004 and tested their serum leptin levels, took anthropometric measurements and calculated BMI. A follow‐up study was carried out to evaluate the BMI of 89 of these infants in childhood, in relation to their serum leptin levels in infancy, at a median (interquartile range) age of 8.8 years (7.8–10.2). The statistical significance of this multivariate analysis was set at p 
ISSN:0803-5253
1651-2227
DOI:10.1111/apa.12354