Association of G197 Polymorphism of IL-17A Gene with Myocardial Remodeling and Aerobic Performance in Athletes

We studied the relationship between G197A polymorphism of IL-17A gene and changes in morphometric echocardiography parameters and physiological parameters in skiers (19 examinees). Genotyping was performed by restriction fragment length polymorphism analysis and echocardiography using a Nemio MX ult...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2014-09, Vol.157 (5), p.659-662
Hauptverfasser:	Lifanov, A. D., Khadyeva, M. N., Demenev, S. V., Knyazev, A. N., Babushkin, Yu. A., Astashina, E. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Athletes Biomedical and Life Sciences Biomedicine Cell Biology Exercise Female Genetic aspects Genetic polymorphisms Heart - anatomy & histology Heart - physiology Humans Interleukin-17 - genetics Internal Medicine Laboratory Medicine Male Pathology Physiological aspects Polymorphism, Genetic Sports Young Adult
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Beschreibung
Zusammenfassung:	We studied the relationship between G197A polymorphism of IL-17A gene and changes in morphometric echocardiography parameters and physiological parameters in skiers (19 examinees). Genotyping was performed by restriction fragment length polymorphism analysis and echocardiography using a Nemio MX ultrasound scanner (Toshiba). Association of 197A allele of IL-17A gene with low myocardial growth and high aerobic performance of athletes was demonstrated.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-014-2638-2