Manganese(I)‐Catalyzed Regioselective C−H Allenylation: Direct Access to 2‐Allenylindoles

A MnI‐catalyzed regioselective C−H allenylation is reported that allows a broad range of 2‐allenylindoles to be synthesized regioselectively on a gram scale under simple conditions. Notably, a highly efficient chirality transfer was observed (up to 93 % ee) in this transformation. This procedure was...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-06, Vol.56 (23), p.6660-6664
Hauptverfasser:	Lu, Qingquan, Greßies, Steffen, Klauck, Felix J. R., Glorius, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Activation analysis allenylindoles Carbon Carbonates Chemical bonds Chirality C−H activation enantioselectivity Ketones Manganese manganese catalysis Oxygen Regioselectivity Synthesis
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