Risk Factors and Outcomes Related to Pediatric Intensive Care Unit Admission after Hematopoietic Stem Cell Transplantation: a Single Centre Experience

Highlights • We studied a cohort of 496 children undergoing HSCT in a single center. • The 3-year cumulative incidence of PICU admission was 14.3%. • Risk factors for PICU admission were allogeneic HSCT and second or third HSCT. • 90-day probability of survival after PICU admission for HSCT was 34.3...

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Veröffentlicht in:	Biology of blood and marrow transplantation 2017-08, Vol.23 (8), p.1335-1341
Hauptverfasser:	Pillon, Marta, MD, Amigoni, Angela, MD, Contin, Annaelena, MD, Cattelan, Manuela, PhD, Carraro, Elisa, BS, Campagnano, Emiliana, MD, Tumino, Manuela, MD, Calore, Elisabetta, MD, Marzollo, Antonio, MD, Mainardi, Chiara, MD, Boaro, Maria Paola, MD, Nizzero, Marta, MD, Pettenazzo, Andrea, MD, Basso, Giuseppe, MD, Messina, Chiara, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allografts Bone marrow transplantation Child Child, Preschool Critical Care Disease-Free Survival Female Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cell Transplantation Humans Incidence Infant Male Mortality Multiple Organ Failure - etiology Multiple Organ Failure - mortality Multiple Organ Failure - therapy Outcome Patient Admission Pediatric intensive care unit Respiratory Insufficiency - etiology Respiratory Insufficiency - mortality Respiratory Insufficiency - therapy Retrospective Studies Risk Factors Shock, Septic - etiology Shock, Septic - mortality Shock, Septic - therapy Survival Rate
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Beschreibung
Zusammenfassung:	Highlights • We studied a cohort of 496 children undergoing HSCT in a single center. • The 3-year cumulative incidence of PICU admission was 14.3%. • Risk factors for PICU admission were allogeneic HSCT and second or third HSCT. • 90-day probability of survival after PICU admission for HSCT was 34.3%. • Relapse, mismatched HSCT, lung or hepatic failure were associated with mortality.
ISSN:	1083-8791 1523-6536
DOI:	10.1016/j.bbmt.2017.04.016