Splicing regulatory factors, ageing and age-related disease
Highlights • Alternative splicing (AS) is emerging as an important control point of gene expression. • AS allows a single gene to produce several mRNA with diverse biological functions. • AS is deregulated during ageing. • Aberrant AS has deep implications for age-related disease.
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| Veröffentlicht in: | Ageing research reviews 2017-07, Vol.36, p.165-170 |
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| container_end_page | 170 |
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| container_title | Ageing research reviews |
| container_volume | 36 |
| creator | Latorre, Eva Harries, Lorna. W |
| description | Highlights • Alternative splicing (AS) is emerging as an important control point of gene expression. • AS allows a single gene to produce several mRNA with diverse biological functions. • AS is deregulated during ageing. • Aberrant AS has deep implications for age-related disease. |
| doi_str_mv | 10.1016/j.arr.2017.04.004 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Ageing research reviews, 2017-07, Vol.36, p.165-170 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Aging - genetics Aging - metabolism Aging - pathology Alternative Splicing - physiology Animals Cardiovascular Diseases - genetics Cardiovascular Diseases - metabolism Heterogeneous-Nuclear Ribonucleoprotein Group A-B - genetics Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism Humans Internal Medicine Neurology RNA, Messenger - genetics |
| title | Splicing regulatory factors, ageing and age-related disease |
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