The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications
A novel zwitterionic near-infrared (NIR) dye, ZWCC, has been designed and synthesized. It shows significantly enhanced photostability and chemical stability compared to the existing zwitterionic NIR dye. In addition, the feasibility of labeling ZWCC with biological ligands was investigated and used...
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2015-03, Vol.51 (19), p.3989-3992 |
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container_title | Chemical communications (Cambridge, England) |
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creator | Su, Dongdong Teoh, Chai Lean Samanta, Animesh Kang, Nam-Young Park, Sung-Jin Chang, Young-Tae |
description | A novel zwitterionic near-infrared (NIR) dye, ZWCC, has been designed and synthesized. It shows significantly enhanced photostability and chemical stability compared to the existing zwitterionic NIR dye. In addition, the feasibility of labeling ZWCC with biological ligands was investigated and used in live cell imaging applications. |
doi_str_mv | 10.1039/c4cc08814j |
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source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Cell Survival Corrosion resistance Drug Design Drug Stability Dyes Feasibility Fluorescent Dyes - chemistry Humans Imaging Infrared Rays Labels Ligands Marking MCF-7 Cells Molecular Imaging - methods Peptides, Cyclic - chemistry Synthesis |
title | The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications |
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