An injectable thermogel with high radiopacity

An injectable thermogel with high radiopacity

An injectable PEG/polyester thermogel with strong X-ray opacity was designed and synthesized through the conjugation of 2,3,5-triiodobenzoic acid to the hydrophobic end of the mPEG-PLA diblock copolymer for the first time.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2015-04, Vol.51 (28), p.6080-6083
Hauptverfasser: Lei, Kewen, Shen, Wenjia, Cao, Luping, Yu, Lin, Ding, Jiandong
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Conjugation
Copolymers
Drug Delivery Systems
Gels - administration & dosage
Gels - chemical synthesis
Gels - chemistry
Mice
Mice, Inbred ICR
Opacity
Polyester resins
Polyesters - administration & dosage
Polyesters - chemistry
Polyethylene Glycols - administration & dosage
Polyethylene Glycols - chemistry
Radiopacity
Synthesis (chemistry)
Temperature
Tomography, X-Ray Computed
X rays
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Beschreibung
Zusammenfassung:An injectable PEG/polyester thermogel with strong X-ray opacity was designed and synthesized through the conjugation of 2,3,5-triiodobenzoic acid to the hydrophobic end of the mPEG-PLA diblock copolymer for the first time.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc00049a