Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling

Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling

This work describes a novel mono-boronic acid derivative of a tricarbocyanine. The probe is a genuine near-infrared fluorescence emitter with improved properties such as a large Stokes shift, excellent water solubility and sensitive fluorogenicity upon binding to carbohydrates under physiological co...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2015-03, Vol.51 (23), p.4895-4898
Hauptverfasser: Samaniego Lopez, Cecilia, Lago Huvelle, María Amparo, Uhrig, María Laura, Coluccio Leskow, Federico, Spagnuolo, Carla C
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Binding
Boron Compounds - chemistry
Carbohydrates
Carbohydrates - chemistry
Cell Line
Derivatives
Fluid flow
Fluorescence
Fluorescent Dyes - chemistry
Molecular Structure
Monosaccharides - chemistry
Recognition
Saccharides
Sensitivity and Specificity
Solubility
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Beschreibung
Zusammenfassung:This work describes a novel mono-boronic acid derivative of a tricarbocyanine. The probe is a genuine near-infrared fluorescence emitter with improved properties such as a large Stokes shift, excellent water solubility and sensitive fluorogenicity upon binding to carbohydrates under physiological conditions.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc10425k