Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynes

Palladium-catalyzed synthesis of polysubstituted quinolines from 2-amino aromatic ketones and alkynes

A palladium-catalyzed one-pot method for the synthesis of quinolines from commercial or readily available 2-amino aromatic ketones and alkynes is reported for the first time. This transformation offers an alternative method for the synthesis of polysubstituted quinoline.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2014-05, Vol.50 (42), p.5583-5585
Hauptverfasser: Zhou, Wang, Lei, Jianhua
Format: Artikel
Sprache:eng
Schlagworte:
Alkynes
Alkynes - chemistry
Catalysis
Chemistry Techniques, Synthetic
Ketones
Ketones - chemistry
Organic compounds
Palladium
Palladium - chemistry
Quinolines - chemical synthesis
Quinolines - chemistry
Synthesis
Transformations
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Beschreibung
Zusammenfassung:A palladium-catalyzed one-pot method for the synthesis of quinolines from commercial or readily available 2-amino aromatic ketones and alkynes is reported for the first time. This transformation offers an alternative method for the synthesis of polysubstituted quinoline.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc00939h