Converting oxazoles into imidazoles: new opportunities for diversity-oriented synthesis

We report the optimization of a neglected reaction for the rapid and direct conversion of oxazoles into N-substituted imidazoles. The utility of this microwave-promoted reaction for diversity-oriented synthesis is demonstrated in the preparation of >40 N-substituted imidazoles, including α-imidaz...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-01, Vol.50 (15), p.1867-1870
Hauptverfasser:	Alzieu, Thibaut, Lehmann, Johannes, Naidu, Ajay B, Martin, Rainer E, Britton, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Techniques, Synthetic Converting Direct conversion Esters Imidazole Imidazoles - chemical synthesis Imidazoles - chemistry Microwaves Optimization Oxazole Oxazoles - chemistry Synthesis Utilities
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