Sensitive and portable detection of telomerase activity in HeLa cells using the personal glucose meter

Using the personal glucose meter, a portable sensor was fabricated to assay telomerase activity and study the telomerase inhibitor AZT. Hence, it provided a promising approach for the detection of enzyme activity and diagnosis of cancer.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-07, Vol.50 (58), p.7897-7899
Hauptverfasser:	Zhu, Xi, Xu, Huifeng, Lin, Ruolan, Yang, Guidi, Lin, Zhenyu, Chen, Guonan
Format:	Artikel
Sprache:	eng
Schlagworte:	AZT Biosensing Techniques - instrumentation Cancer Diagnosis Glucose HeLa Cells Humans Measuring instruments Medical devices Portability Sensors Telomerase Telomerase - antagonists & inhibitors Telomerase - metabolism Zidovudine - pharmacology
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Beschreibung
Zusammenfassung:	Using the personal glucose meter, a portable sensor was fabricated to assay telomerase activity and study the telomerase inhibitor AZT. Hence, it provided a promising approach for the detection of enzyme activity and diagnosis of cancer.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c4cc03553d