A ratiometric fluorescent probe with unexpected high selectivity for ATP and its application in cell imaging

Naphthalimide-rhodamine compound (NR) is developed as a ratiometric fluorescent probe for ATP detection based on the FRET mechanism. It shows an unexpected high selectivity for ATP over other anions, especially organic phosphate anions, due to simultaneous interactions of two recognition sites, whic...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-12, Vol.50 (97), p.15411-15414
Hauptverfasser:	Tang, Jia-Liang, Li, Chun-Yan, Li, Yong-Fei, Zou, Chun-Xiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - analysis Adenosine Triphosphate - chemistry Anions Cells (biology) Colorimetry Fluorescence Fluorescence Resonance Energy Transfer Fluorescent Dyes - chemistry Fretting HeLa Cells Humans Imaging Naphthalimides - chemistry Optical Imaging Phosphates Recognition Rhodamines - chemistry Selectivity
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Beschreibung
Zusammenfassung:	Naphthalimide-rhodamine compound (NR) is developed as a ratiometric fluorescent probe for ATP detection based on the FRET mechanism. It shows an unexpected high selectivity for ATP over other anions, especially organic phosphate anions, due to simultaneous interactions of two recognition sites, which benefits fluorescence imaging in living cells.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c4cc08044k