Differences in mortality characteristics in neonates with Down’s syndrome

Objective: Neonates with Down’s syndrome (nDS) may have multiple medical issues that place them at increased risk for mortality during the newborn period. Goal of this study was to determine if there are differences in baseline characteristics, medical complications or procedures performed during ho...

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Veröffentlicht in:	Journal of perinatology 2017-04, Vol.37 (4), p.427-431
Hauptverfasser:	Cua, C L, Haque, U, Santoro, S, Nicholson, L, Backes, C H
Format:	Artikel
Sprache:	eng
Schlagworte:	692/499 Birth weight Cause of Death Complications Databases, Factual Demographics Demography Diagnosis Diseases Down syndrome Down Syndrome - complications Down Syndrome - mortality Down Syndrome - therapy Down's syndrome Enterocolitis Enterocolitis, Necrotizing - epidemiology Extracorporeal Membrane Oxygenation - methods Female Gastrointestinal diseases Gestational age Heart Heart Defects, Congenital - epidemiology Hernia Hernias, Diaphragmatic, Congenital - epidemiology Hospitalization Hospitals Humans Infant Infant, Newborn Infants (Newborn) Information systems Logistic Models Male Mechanical ventilation Medicine Medicine & Public Health Mortality Multivariate Analysis Necrosis Necrotizing enterocolitis Neonates Newborn babies original-article Oxygenation Patient outcomes Patients Pediatric Surgery Pediatrics Population Respiration, Artificial - methods Retrospective Studies Risk Risk factors United States - epidemiology
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Beschreibung
Zusammenfassung:	Objective: Neonates with Down’s syndrome (nDS) may have multiple medical issues that place them at increased risk for mortality during the newborn period. Goal of this study was to determine if there are differences in baseline characteristics, medical complications or procedures performed during hospitalization between nDS who survived versus those who died during initial hospitalization. Study Design: Data from 2000 to 2014 were reviewed using the Pediatric Health Information Systems (PHIS) database on all DS patients admitted to the hospital
ISSN:	0743-8346 1476-5543
DOI:	10.1038/jp.2016.246