Lung function not affected by asbestos exposure in workers with normal Computed Tomography scan
Background: It has been suggested that asbestos exposure affects lung function, even in the absence of asbestos‐related pulmonary interstitial or pleural changes or emphysema. Methods: We analyzed associations between well‐known asbestos‐related risk factors, such as individual cumulative asbestos e...
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Veröffentlicht in: | American journal of industrial medicine 2017-05, Vol.60 (5), p.422-431 |
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Zusammenfassung: | Background: It has been suggested that asbestos exposure affects lung function, even in the absence of asbestos‐related pulmonary interstitial or pleural changes or emphysema. Methods: We analyzed associations between well‐known asbestos‐related risk factors, such as individual cumulative asbestos exposure, and key lung function parameters in formerly asbestos‐exposed power industry workers (N = 207) with normal CT scans. For this, we excluded participants with emphysema, fibrosis, pleural changes, or any combination of these. Results: The lung function parameters of FVC, FEV1, DLCO/VA, and airway resistance were significantly associated with the burden of smoking, BMI and years since end of exposure (only DLCO/VA). However, they were not affected by factors directly related to amount (eg, cumulative exposure) or duration of asbestos exposure. Conclusions: Our results confirm the well‐known correlation between lung function, smoking habits, and BMI. However, we found no significant association between lung function and asbestos exposure. |
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ISSN: | 0271-3586 1097-0274 |
DOI: | 10.1002/ajim.22717 |