Predictors of a successful outcome for infants with short bowel syndrome: a 30-year single-institution experience

Predictors of a successful outcome for infants with short bowel syndrome: a 30-year single-institution experience

Purpose Short-bowel syndrome (SBS) is associated with high morbidity and mortality. We conducted this study to establish the predictors of survival and weaning off parenteral nutrition (PN). Methods We reviewed the medical records of 16 SBS infants treated at our institution within a 30-year period....

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Veröffentlicht in:Surgery today (Tokyo, Japan) Japan), 2017-11, Vol.47 (11), p.1391-1396
Hauptverfasser: Kaji, Tatsuru, Nakame, Kazuhiko, Machigashira, Seiro, Kawano, Takafumi, Masuya, Ryuta, Yamada, Waka, Yamada, Koji, Onishi, Shun, Moriguchi, Tomoe, Sugita, Koshiro, Mukai, Motoi, Ieiri, Satoshi
Format: Artikel
Sprache:eng
Schlagworte:
Child
Child, Preschool
Cholestasis - etiology
Forecasting
Humans
Hypokalemia - etiology
Infant
Infant, Newborn
Intestine, Small - transplantation
Male
Medicine
Medicine & Public Health
Original Article
Parenteral Nutrition
Retrospective Studies
Short Bowel Syndrome - mortality
Short Bowel Syndrome - surgery
Short Bowel Syndrome - therapy
Surgery
Surgical Oncology
Survival Rate
Time Factors
Treatment Outcome
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Zusammenfassung:Purpose Short-bowel syndrome (SBS) is associated with high morbidity and mortality. We conducted this study to establish the predictors of survival and weaning off parenteral nutrition (PN). Methods We reviewed the medical records of 16 SBS infants treated at our institution within a 30-year period. SBS was defined as a residual small-bowel length (RSBL) of 2.0 mg/dl), enterostomy, and RSBL were all evaluated. Kaplan–Meier analysis was used to analyze the predictors. Results The mean RSBL was 34.9 ± 22.9 cm. Six patients died (37.5%) and nine patients were weaned off PN (56.3%). Significant differences were observed in cholestasis ( p  
ISSN:0941-1291
1436-2813
DOI:10.1007/s00595-017-1534-6