Exercise-modulated epigenetic markers and inflammatory response in COPD individuals: a pilot study

Highlights • A DNA hypomethylation status was found after the 1st PRP session in COPD patients. • No significant changes were observed on cytokine levels after the 1st PRP session. • The PRP did not alter global histone H4 acetylation levels in COPD patients. • 24 sessions of PRP reduced IL-6 and IL...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2017-08, Vol.242, p.89-95
Hauptverfasser:	da Silva, Ivy Reichert Vital, de Araujo, Cintia Laura Pereira, Dorneles, Gilson Pires, Peres, Alessandra, Bard, Andreia Luciana, Reinaldo, Gustavo, Teixeira, Paulo José Zimermann, Lago, Pedro Dal, Elsner, Viviane Rostirola
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Aged Biomarkers - blood COPD Cytokines - blood DNA Methylation Dyspnea - blood Dyspnea - genetics Dyspnea - immunology Dyspnea - rehabilitation Epigenesis, Genetic Exercise Exercise - physiology Exercise Therapy Female Global DNA methylation Global histone H4 acetylation Histones - blood Humans Inflammatory response Male Medical Education Pilot Projects Pulmonary Disease, Chronic Obstructive - blood Pulmonary Disease, Chronic Obstructive - genetics Pulmonary Disease, Chronic Obstructive - immunology Pulmonary Disease, Chronic Obstructive - rehabilitation Pulmonary/Respiratory Quality of Life Sedentary Lifestyle Treatment Outcome
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