Shear Wave Liver Elastography with a Propagation Map: Diagnostic Performance and Inter-Observer Correlation for Hepatic Fibrosis in Chronic Hepatitis

Abstract The aim of this study was to determine the performance of shear wave elastography (SWE) with a propagation map in the diagnosis of hepatic fibrosis, and to assess its reliability with transient elastography (TE) as the reference standard. Our prospective study included 115 consecutive patie...

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Veröffentlicht in:Ultrasound in medicine & biology 2017-07, Vol.43 (7), p.1355-1363
Hauptverfasser: Lee, Eun Sun, Lee, Jong Beum, Park, Hwi Ryong, Yoo, Jeongin, Choi, Ji In, Lee, Hyun Woong, Kim, Hyung Joon, Choi, Byung Ihn, Park, Hyun Jeong, Park, Sung Bin
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Sprache:eng
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Zusammenfassung:Abstract The aim of this study was to determine the performance of shear wave elastography (SWE) with a propagation map in the diagnosis of hepatic fibrosis, and to assess its reliability with transient elastography (TE) as the reference standard. Our prospective study included 115 consecutive patients with suspected or alleged chronic hepatitis. Patients underwent SWE by two different operators and TE by sonographers on the same day. The correlation coefficient of the intra-class correlation test between an experienced radiologist and a third-year radiology resident was 0.878. There was a moderate correlation between SWE and TE ( r  = 0.511) in the diagnosis of hepatic fibrosis. The best cutoff values predicting significant hepatic fibrosis and liver cirrhosis by SWE were >1.78 m/s (area under the receiver operating characteristic curve [AUROC] = 0.777) and >2.24 m/s (AUROC = 0.935), respectively. SWE with a propagation map is a reliable method for predicting hepatic fibrosis regardless of operator experience.
ISSN:0301-5629
1879-291X
DOI:10.1016/j.ultrasmedbio.2017.02.010