Effect of Preparation Based on Trametes Pubescens Xylotroph Fungi on Lipid Peroxidation in the Blood of Experimental Animals under Conditions of Dark Stress

Using the model of dark stress caused by animal maintenance at dimmed light we showed that Trametin (product obtained during liquid-phase culturing of Trametes pubescens xylotroph fungi) effectively prevented oxidative stress under conditions of light deprivation. The preparation increased the level...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2017-04, Vol.162 (6), p.762-764
Hauptverfasser: Kolesnikova, L. I., Kolesnikov, S. I., Romanova, E. D., Chkhenkeli, V. A., Darenskaya, M. A., Grebenkina, L. A., Korytov, L. I., Bugun, O. V., Koroleva, N. V., Gutnik, I. N., Antonenko, F. F.
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Sprache:eng
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Zusammenfassung:Using the model of dark stress caused by animal maintenance at dimmed light we showed that Trametin (product obtained during liquid-phase culturing of Trametes pubescens xylotroph fungi) effectively prevented oxidative stress under conditions of light deprivation. The preparation increased the level of unsaturation of lipids, reduced the concentration of primary and end-products of LPO, and increases both the integral parameter of the antioxidant defense system (total antioxidant activity) and its components (activity of superoxide dismutase and reduced glutathione).
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-017-3707-0