Four New Diterpene Glucosides from Perovskia atriplicifolia

Four new diterpene glucosides, namely perovskiaditerpenosides A – D (1 – 4), were isolated from the BuOH extract of Perovskia atriplicifolia. Their structures were well elucidated by chemical methods and comprehensive spectroscopic analyses including MS, IR, and NMR (1D and 2D). The newly isolated c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemistry & biodiversity 2017-07, Vol.14 (7), p.n/a
Hauptverfasser:	Gao, Lu, Zhou, Jun, Zhu, Le‐Yu, Zhang, Juan‐Rong, Jing, Yu‐Xing, Zhao, Jia‐Wen, Huang, Xiang‐Zhong, Li, Gan‐Peng, Jiang, Zhi‐Yong, Xue, Da‐Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Butanols Cell Line, Tumor Cytotoxic activities Cytotoxicity Diterpene glucosides Diterpenes - isolation & purification Drug Screening Assays, Antitumor Glucosides Glucosides - isolation & purification Humans Infrared spectroscopy Labiatae Lamiaceae - chemistry Molecular Structure NMR Nuclear magnetic resonance Perovskia atriplicifolia Perovskiaditerpenosides A – D Plant Extracts Spectroscopic analysis Spectrum Analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Four new diterpene glucosides, namely perovskiaditerpenosides A – D (1 – 4), were isolated from the BuOH extract of Perovskia atriplicifolia. Their structures were well elucidated by chemical methods and comprehensive spectroscopic analyses including MS, IR, and NMR (1D and 2D). The newly isolated compounds were screened for their cytotoxic activity against HepG2, NB4, HeLa, K562, MCF7, PC3, and HL60. The obtained results indicated that the new compounds possessed considerable cytotoxic activity.
ISSN:	1612-1872 1612-1880
DOI:	10.1002/cbdv.201700071