Impact Of Diabetes Mellitus On Ischemic Events In Men And Women After Percutaneous Coronary Intervention

Abstract Studies have shown worse outcome for women compared with men after percutaneous coronary intervention (PCI), especially in the presence of diabetes mellitus (DM). We aimed to investigate the risk of ischemic events after PCI in women versus men stratified by the presence or absence of DM. A...

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Veröffentlicht in:	The American journal of cardiology 2017-04, Vol.119 (8), p.1166-1172
Hauptverfasser:	Farhan, Serdar, MD, Baber, Usman, MD, MS, Vogel, Birgit, MD, Aquino, Melissa, MS, Chandrasekhar, Jaya, MBBS, Faggioni, Michela, MD, Giustino, Gennaro, MD, Kautzky-Willer, Alexandra, MD, Sweeny, Joesph, MD, Shah, Srushti, MD, Vijay, Pooja, MD, Barman, Nitin, MD, Moreno, Pedro, MD, Kovacic, Jason, MD, PhD, Dangas, George, MD, PhD, Kini, Annapoorna, MD, Mehran, Roxana, MD, Sharma, Samin, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angioplasty C-Reactive Protein - analysis Cardiovascular Cardiovascular disease Coronary Artery Disease - mortality Coronary Artery Disease - therapy Death Diabetes Diabetes mellitus Diabetes Mellitus - epidemiology Female Follow-Up Studies Glycated Hemoglobin A - analysis Health risk assessment Humans Intervention Ischemia Male Men Middle Aged Mortality Multivariate Analysis Myocardial infarction Myocardial Infarction - epidemiology New York - epidemiology Percutaneous Coronary Intervention Registries Retrospective Studies Risk Risk Assessment Sex Factors Stents Womens health
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Zusammenfassung:	Abstract Studies have shown worse outcome for women compared with men after percutaneous coronary intervention (PCI), especially in the presence of diabetes mellitus (DM). We aimed to investigate the risk of ischemic events after PCI in women versus men stratified by the presence or absence of DM. A total of 17,154 consecutive patients from a single center PCI registry enrolled between January 2009 and December 2014 were categorized accordingly: female/non-DM, female/DM, male/non-DM and male/DM. Endpoints included death and myocardial infarction (MI) at 1 year. Of the overall population, 15% (n=2631) were female/non-DM, 17% (n=2891) were female/DM, 38% (n=6483) were male/non-DM and 30% (n=5149) were male/DM. Within the four study groups, female/DM had the highest risk, while female/non-DM and male/DM showed similar risks and male/non-DM showed lowest risk for death (4.64% vs. 3.08% vs. 2.93% vs. 2.31%; p-trend
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2016.12.035