Desensitization to DNFB in hairless mice
Naive hairless mice may be rendered partly tolerant to dinitrofluorobenzene (DNFB) by painting UNFB on skin irradiated with 30 mJ·cm−2 ultraviolet B light (UVB) over 4 days. However, DNFB‐sensitized hairless mice show no decrease in sensitivity when repainted with DNFB on skin irradiated with the sa...
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| Veröffentlicht in: | Contact dermatitis 1987-09, Vol.17 (3), p.146-148 |
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| container_title | Contact dermatitis |
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| creator | Copeman, M. C. |
| description | Naive hairless mice may be rendered partly tolerant to dinitrofluorobenzene (DNFB) by painting UNFB on skin irradiated with 30 mJ·cm−2 ultraviolet B light (UVB) over 4 days. However, DNFB‐sensitized hairless mice show no decrease in sensitivity when repainted with DNFB on skin irradiated with the same dose of UVB. Hence, established hypersensitivity appears not lo be reduced by this method of inducing tolerance in nuive mice. |
| doi_str_mv | 10.1111/j.1600-0536.1987.tb02694.x |
| format | Article |
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C.</creator><creatorcontrib>Copeman, M. C.</creatorcontrib><description>Naive hairless mice may be rendered partly tolerant to dinitrofluorobenzene (DNFB) by painting UNFB on skin irradiated with 30 mJ·cm−2 ultraviolet B light (UVB) over 4 days. However, DNFB‐sensitized hairless mice show no decrease in sensitivity when repainted with DNFB on skin irradiated with the same dose of UVB. Hence, established hypersensitivity appears not lo be reduced by this method of inducing tolerance in nuive mice.</description><identifier>ISSN: 0105-1873</identifier><identifier>EISSN: 1600-0536</identifier><identifier>DOI: 10.1111/j.1600-0536.1987.tb02694.x</identifier><identifier>PMID: 3677657</identifier><identifier>CODEN: CODEDG</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Allergic diseases ; Animals ; Biological and medical sciences ; contact hypersensitivity ; Dermatitis, Contact - immunology ; Dermatitis, Contact - radiotherapy ; Desensitization, Immunologic ; Dinitrofluorobenzene - adverse effects ; Female ; Hairless mice ; Immune Tolerance ; Immunopathology ; Male ; Medical sciences ; Mice ; Mice, Hairless ; Nitrobenzenes - adverse effects ; Skin allergic diseases. 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C.</creatorcontrib><title>Desensitization to DNFB in hairless mice</title><title>Contact dermatitis</title><addtitle>Contact Dermatitis</addtitle><description>Naive hairless mice may be rendered partly tolerant to dinitrofluorobenzene (DNFB) by painting UNFB on skin irradiated with 30 mJ·cm−2 ultraviolet B light (UVB) over 4 days. However, DNFB‐sensitized hairless mice show no decrease in sensitivity when repainted with DNFB on skin irradiated with the same dose of UVB. Hence, established hypersensitivity appears not lo be reduced by this method of inducing tolerance in nuive mice.</description><subject>Allergic diseases</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>contact hypersensitivity</subject><subject>Dermatitis, Contact - immunology</subject><subject>Dermatitis, Contact - radiotherapy</subject><subject>Desensitization, Immunologic</subject><subject>Dinitrofluorobenzene - adverse effects</subject><subject>Female</subject><subject>Hairless mice</subject><subject>Immune Tolerance</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Hairless</subject><subject>Nitrobenzenes - adverse effects</subject><subject>Skin allergic diseases. Stinging insect allergies</subject><subject>ultraviolet B irradiation</subject><subject>Ultraviolet Therapy</subject><issn>0105-1873</issn><issn>1600-0536</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF1LwzAUhoMoOqc_QSjixW5aTz6aZF4Iuukm6oageBnSLMXMrp1Nh9Nfb8bK7s3NuTjPefPyIHSOIcHhXc4TzAFiSClPcF-KpMmA8D5L1nuos1vtow5gSGMsBT1Cx97PATBnRB6iQ8qF4KnooN7Qelt617hf3biqjJoqGk7ubyNXRh_a1YX1Plo4Y0_QQa4Lb0_b2UVv93evg3H8NB09DG6eYsMw4TFLM20IzQnVOme5xZxIkllOgEkzg75INQNuCKGhcZprm0kbCJgJzoFxoF3U2-Yu6-prZX2jFs4bWxS6tNXKKyyl7If2lAT0aouauvK-trla1m6h6x-FQW1Eqbna2FAbG2ojSrWi1Docn7X_rLKFne1OWzNhf9HutTe6yGtdGud3mEgxY0ADdr3Fvl1hf_5RQA2mQ8x4CIi3Ac43dr0L0PWn4oKKVL1PRmr8PHin8hHUC_0Du7uRFg</recordid><startdate>198709</startdate><enddate>198709</enddate><creator>Copeman, M. 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Stinging insect allergies</topic><topic>ultraviolet B irradiation</topic><topic>Ultraviolet Therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Copeman, M. C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Contact dermatitis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Copeman, M. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Desensitization to DNFB in hairless mice</atitle><jtitle>Contact dermatitis</jtitle><addtitle>Contact Dermatitis</addtitle><date>1987-09</date><risdate>1987</risdate><volume>17</volume><issue>3</issue><spage>146</spage><epage>148</epage><pages>146-148</pages><issn>0105-1873</issn><eissn>1600-0536</eissn><coden>CODEDG</coden><abstract>Naive hairless mice may be rendered partly tolerant to dinitrofluorobenzene (DNFB) by painting UNFB on skin irradiated with 30 mJ·cm−2 ultraviolet B light (UVB) over 4 days. However, DNFB‐sensitized hairless mice show no decrease in sensitivity when repainted with DNFB on skin irradiated with the same dose of UVB. 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| identifier | ISSN: 0105-1873 |
| ispartof | Contact dermatitis, 1987-09, Vol.17 (3), p.146-148 |
| issn | 0105-1873 1600-0536 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Allergic diseases Animals Biological and medical sciences contact hypersensitivity Dermatitis, Contact - immunology Dermatitis, Contact - radiotherapy Desensitization, Immunologic Dinitrofluorobenzene - adverse effects Female Hairless mice Immune Tolerance Immunopathology Male Medical sciences Mice Mice, Hairless Nitrobenzenes - adverse effects Skin allergic diseases. Stinging insect allergies ultraviolet B irradiation Ultraviolet Therapy |
| title | Desensitization to DNFB in hairless mice |
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