Delayed hypersensitivity drug reactions diagnosed by patch testing

Drug reactions area common problem in hospital inpatients and outpatients. Oral or parenteral drug challenges are valuable diagnostic aids, but time consuming. We review attempts to diagnose delayed hypersensitivity drug eruptions by patch testing. We review control data, and offer an operational de...

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Veröffentlicht in:	Contact dermatitis 1993-11, Vol.29 (5), p.223-233
Hauptverfasser:	Marie Calkin, Jacqueline, Maibach, Howard I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biological and medical sciences carbamazepine delayed hypersensitivity diagnostic criteria Drug Eruptions - diagnosis Drug Eruptions - etiology Drug Hypersensitivity - diagnosis Drug Hypersensitivity - etiology drug reactions Drug toxicity and drugs side effects treatment Female Humans Hypersensitivity, Delayed - chemically induced Hypersensitivity, Delayed - diagnosis irritant controls Male man Medical sciences Middle Aged Miscellaneous (drug allergy, mutagens, teratogens...) patch testing Patch Tests Pharmacology. Drug treatments practolol pyrazolines tetrazepam
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Beschreibung
Zusammenfassung:	Drug reactions area common problem in hospital inpatients and outpatients. Oral or parenteral drug challenges are valuable diagnostic aids, but time consuming. We review attempts to diagnose delayed hypersensitivity drug eruptions by patch testing. We review control data, and offer an operational definition that might make for greater acceptance of the rôle of diagnostic patch testing in this entity.
ISSN:	0105-1873 1600-0536
DOI:	10.1111/j.1600-0536.1993.tb03555.x