Endothelin Polymorphisms as a Risk Factor for Cerebral Aneurysm Rebleeding Following Aneurysmal Subarachnoid Hemorrhage

Highlights • Aneurysm rebleeding is a significant risk for patients presenting with aSAH. • Rebleeding is associated with the TT genotype of the EDN1 G/T SNP. • Patients suffering from rebleeding experience poor functional outcomes.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical neurology and neurosurgery 2017-06, Vol.157, p.65-69
Hauptverfasser:	Foreman, Paul M, Starke, Robert M, Hendrix, Philipp, Harrigan, Mark R, Fisher, Winfield S, Vyas, Nilesh A, Lipsky, Robert H, Lin, Minkuan, Walters, Beverly C, Pittet, Jean-Francois, Mathru, Mali, Griessenauer, Christoph J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Aneurysm Aneurysms Angiography Angiotensin Assaying Biochemistry Blood pressure Body mass Body mass index Brain Ischemia - genetics Cardiovascular system Cerebral infarction Cerebrospinal fluid Circulation Clinical trials Coma Computed tomography Endothelin Endothelins - genetics Female Genomes Genotype Health risks Hemorrhage Hum Humans Hydrocephalus Hypertension Hypoxia Incidence Intracranial Aneurysm - complications Intracranial Aneurysm - genetics Intracranial pressure Ischemia Male Medical imaging Middle Aged Mortality Neurology Neurosurgery Nimodipine Outcome Polymorphism Polymorphism, Single Nucleotide - genetics Rebleeding Rerupture Risk Factors Rupture Statistical analysis Stroke Subarachnoid Hemorrhage Subarachnoid Hemorrhage - etiology Subarachnoid Hemorrhage - genetics Vasoconstriction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Aneurysm rebleeding is a significant risk for patients presenting with aSAH. • Rebleeding is associated with the TT genotype of the EDN1 G/T SNP. • Patients suffering from rebleeding experience poor functional outcomes.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2017.04.007