Maternal hypothyroxinaemia in early pregnancy and problem behavior in 5-year-old offspring

Highlights • Maternal hypothyroxinaemia in early pregnancy might be associated with hyperactivity/inattention in offspring at age 5, analogous to previous studies. • We have added that maternal thyroid function parameters in early pregnancy were not associated with other types of problem behavior in...

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Veröffentlicht in:	Psychoneuroendocrinology 2017-07, Vol.81, p.29-35
Hauptverfasser:	Oostenbroek, Maurits H.W, Kersten, Remco H.J, Tros, Benjamin, Kunst, Anton E, Vrijkotte, Tanja G.M, Finken, Martijn J.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Child, Preschool Endocrinology & Metabolism Female Follow-up studies Gestational Age Humans Longitudinal Studies Male Maternal hypothyroxinemia Mothers Pregnancy Pregnancy Complications - blood Prenatal Exposure Delayed Effects - psychology Problem Behavior Psychiatry Thyroid function Thyroid Function Tests Thyrotropin - blood Thyroxine - blood Young Adult
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Zusammenfassung:	Highlights • Maternal hypothyroxinaemia in early pregnancy might be associated with hyperactivity/inattention in offspring at age 5, analogous to previous studies. • We have added that maternal thyroid function parameters in early pregnancy were not associated with other types of problem behavior in offspring. • The associations found were confined to teacher reports of hyperactivity/inattention. • Causality has not yet been proven.
ISSN:	0306-4530 1873-3360
DOI:	10.1016/j.psyneuen.2017.03.021