Ecological validity of cost-effectiveness models of universal HPV vaccination: A systematic literature review

Highlights • Protective effect of herd immunity allows the selective HPV immunisation of girls. • Models lack of ecological validity, not adequately reflecting sexual preferences. • Selective immunisation is unlikely to achieve the expected level of herd immunity. • Marginally lower herd immunity wo...

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Veröffentlicht in:	Vaccine 2017-05, Vol.35 (20), p.2622-2632
Hauptverfasser:	Favato, Giampiero, Easton, Tania, Vecchiato, Riccardo, Noikokyris, Emmanouil
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Bibliographic data bases Cervical cancer Clinical trials Cost analysis Cost-Benefit Analysis Cost-effectiveness Disease Ecological validity Epidemiology Females Girls Health care Health policy HPV Human papillomavirus Humans Immunization Infections Licenses Literature reviews Males Medical screening Neoplasms - economics Neoplasms - prevention & control Papillomavirus Infections - complications Papillomavirus Infections - economics Papillomavirus Infections - prevention & control Papillomavirus Vaccines - administration & dosage Papillomavirus Vaccines - economics Papillomavirus Vaccines - immunology Population Public health Public health policy Sexual behavior Sexually transmitted diseases STD Universal vaccination Vaccination Vaccination - economics Vaccination - utilization Vaccines Validity Womens health
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Beschreibung
Zusammenfassung:	Highlights • Protective effect of herd immunity allows the selective HPV immunisation of girls. • Models lack of ecological validity, not adequately reflecting sexual preferences. • Selective immunisation is unlikely to achieve the expected level of herd immunity. • Marginally lower herd immunity would make universal vaccination cost-effective. • Population’s features and sexual preferences should inform HPV vaccination models.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2017.03.093